The show has an official science advisor (David Saltzberg) who helps the writers with the science portion of the scripts.
Every main actor has seen Penny nude apart from Howard
Mayim Bialik, who plays Dr. Amy Farrah Fowler, is actually a neuroscientist
And she is the only cast member to actually have a PhD.
Galecki and Cuoco (who play Leonard and Penny) dated in real life
It’s become a “thing” for real scientists to be featured on the show’s whiteboard.
It took only one take for Cuoco and Galecki to film Penny professing her love for Leonard
Leonard is a cellist on the show, but Galecki is a cellist in real life.
Kevin Sussman (who plays comic shop owner Stuart Bloom) actually worked at a comic book store in New York.
A new species of the Brazilian orchid bee was named after Sheldon’s catchphrase, “Bazinga!”
We will probably never know Penny’s last name.
Science enrollment in universities has increased since the show aired
TBBT actually consulted with NASA for Wolowitz’s space story line.
Sheldon actually played the theremin
The Big Bang writers don’t plot the season out too far in advance
Co-creator Bill Prady was a computer programmer before entering the entertainment industry
The show wasn’t pitched in a traditional manner
Melissa Rauch imitates her mother’s naturally high-pitched voice for her character, Bernadette.
Sheldon’s “softy kitty” song is based on a real song
The Big Bang Theory is the most watched TV series in America
The inspiration for Raj’s inability to talk to women expect when drunk was based on Bill Prady’s old co-worker
There was a Big Bang copycat show
The different floors of Sheldon and Leonard’s apartment building are the same set which are just re-dressed for each scene
Sheldon Cooper and Leonard Hofstadter are named after a late TV producer
TBBT creator Chuck Lorre shows ‘vanity cards’ at the end of each show
Penny’s recurring purse – she has used the same one since S1/Ep02.
Kaley Cuoco missed filming two episodes of season four because of a broken leg
Jim Parsons is somewhat different to Sheldon
Mayim had to cover her hand for five episodes in season six due to a car accident
Sheldon wears tops with 73 on and Jim Parson’s was born in 1973
Leonard rarely has any lenses in his glasses
A new genus of rhizostome jellyfish has recently been named Bazinga
Jim and Kaley are the world’s highest paid TV actors
The theme song was written by Canada’s Barenaked Ladies
The show was originally going to be called ‘Lenny, Penny and Kenny’
Amy’s apartment number is 314 in reference to pi
Kayley presented Jim Parsons with his first Golden Globe in 2011
Sheldon Cooper and Jim Parsons are both from Texas
Raj and Bernadette and Howard’s apartments are filmed on the same set and they just redecorate it every time they want to change between the two
Penny’s character was originally going to be a hard-drinking makeup artist
Mayim confirmed that the university the characters work at is based on California Institute of Technology
Will Wheatons house number (1701) is the same as the number of Star Trek’s USS Enterprise: NCC 1701-D
Amy is allergic to avocados
Raj is supposed to only be able to talk to women “when he is drunk” but in most episodes he can do so after one sip of alcohol
So, basically we have just proved what we DID already know
